Virus Variation Resource—recent updates and future directions
نویسندگان
چکیده
Virus Variation (http://www.ncbi.nlm.nih.gov/genomes/VirusVariation/) is a comprehensive, web-based resource designed to support the retrieval and display of large virus sequence datasets. The resource includes a value added database, a specialized search interface and a suite of sequence data displays. Virus-specific sequence annotation and database loading pipelines produce consistent protein and gene annotation and capture sequence descriptors from sequence records then map these metadata to a controlled vocabulary. The database supports a metadata driven, web-based search interface where sequences can be selected using a variety of biological and clinical criteria. Retrieved sequences can then be downloaded in a variety of formats or analyzed using a suite of tools and displays. Over the past 2 years, the pre-existing influenza and Dengue virus resources have been combined into a single construct and West Nile virus added to the resultant resource. A number of improvements were incorporated into the sequence annotation and database loading pipelines, and the virus-specific search interfaces were updated to support more advanced functions. Several new features have also been added to the sequence download options, and a new multiple sequence alignment viewer has been incorporated into the resource tool set. Together these enhancements should support enhanced usability and the inclusion of new viruses in the future.
منابع مشابه
Future Directions for the Organizational Readiness for Knowledge Translation (OR4KT) Tool: Response to Recent Commentaries
متن کامل
Nanomedicine: An Essential Resource in Treatment and Diagnosis of Viral Diseases
The recent outbreak of COVID-19 is considered to be one of the biggest disasters faced in the history which has already killed 211568 and effected 3065739 people across the world (As on 28th April 2020). Thus, there is an alarming need to discuss novel treatment strategies for treatment of such viral outbreaks. Viral diseases affect millions of people around the world, with a major effect on hu...
متن کاملPatient Engagement and its Evaluation Tools – Current Challenges and Future Directions; Comment on “Metrics and Evaluation Tools for Patient Engagement in Healthcare Organization- and System-Level Decision-Making: A Systematic Review”
Considering the growing recognition of the importance of patient engagement in healthcare decisions, research and delivery systems, it is important to ensure high quality and efficient patient engagement evaluation tools. In this commentary, we will first highlight the definition and importance of patient engagement. Then we discuss the psychometric properties of the patient engagement evaluati...
متن کاملEditorial Report of fifteen years contributions to radiological sciences: Future directions and prospects
At the close of the 20th century, fundamental discoveries changed broadly the worlds of physics, biology and medicine. The rapid advancements achieved during recent years, mainly due to revolutionary methodological improvements, have led to an unparalleled explosion of information; often appear to overshadow the earlier works. However as more basic discoveries are made these separate scientific...
متن کاملIntensive home and community interventions.
This article reviews the evidence base for community-based interventions from a systems of care perspective. The article summarizes previous reviews and provides updates and current directions for recent and ongoing studies. As expected, the evidence base is strongest for multisystemic therapy and treatment foster care. A relatively well-developed evidence base is also revealed for case managem...
متن کامل